Uhtaek Oh
Professor
KIST
October 4~7, 2022
It is my great honor to host the 16th Aslla symposium, an International Symposium held on Oct 4~6, 2022 in Gangneung, Korea. The subtitle is “Mechanotransduction and Pain”. Obviously, mechanotransduction is an emerging field of research that focuses on how physical forces in cells or tissues regulate cellular or physiological functions. Mechanotransdution defines the molecular and cellular processes of conversion of various mechanical stimuli to biological functions. Therefore, mechanotransduction mediates numerous body functions such as touch, proprioception, pain, and hearing. Cellular events include embryonic development, stem cell lineage, cell migration, and tumorigenesis. In the Aslla Symposium, recent findingson various mechanotransduction channels will be discussed. In addition, cellular mechanotransduction processes will also be introduced. Pain is another important topic in this symposium. Pain research is critical for maintaining human’s quality life. However, the treatment of chronic pain is not fulfilled, yet, mainly because its etiology is complex. In the symposium, experts from different fields of pain research will introduce novel ideas on pain mechanisms. In addition, novel candidate chemicals for treating chronic pain will be introduced. As world-renowned researchers are invited, this symposium is a good chance to satisfy your hunger for novel theories and ideas. Aslla is an old name of Gangneung city, a port city in the eastern part of Korea. Surrounded by mountains and clean ocean, Gangneung is one of the most popular resorts in Korea. You will enjoy the scenery as well as the symposium. More importantly, the symposium registration is free. You are cordially welcome! Uhtaek Oh, KIST Chair Organizing Committee
Professor
KIST
Professor
University of Toronto
Professor
Heidelberg University
Professor
National University of Singapore
Professor
University College London
Professor
National Institute for
Physiological Sciences
Professor
Harvard University
Professor
Tsinghua University
Professor
Centre National de la Recherche Scientifique
Professor
Victor Chang Cardiac Research Institute
Professor
Institute for Basic Science
| Organizers | |
|---|---|
| Uhtaek Oh | Korea Institute of Science and Technology (KIST) |
| Speakers | |
| Min Zhou | University of Toronto |
| Rohini Kuner | Heidelberg University |
| Yan Jie | National University of Singapore |
| John Wood | Mechanosensation and pain; from genes to drugs |
| Makoto Tominaga | National Institute for Physiological Sciences |
| Jeffrey Holt | Harvard University |
| Bailong Xiao | Tsinghua University |
| Eric Honore | Centre National de la Recherche Scientifique |
| Boris Martinac | Victor Chang Cardiac Research Institute |
| C. Justin Lee | Institute for Basic Science |
| Choong-Wan Woo | Institute for Basic Science |
| Seog Bae OH | Seoul National University |
| Chungho Kim | Korea University |
| Dong-Hwee Kim | Korea University |
| Sun Wook Hwang | Korea University |
| Woongbin Kim | iN Therapeutics |
| Kyuhyung Kim | DGIST |
| Gyusang Hong | Korea Institute of Science and Technology (KIST) |
| Tae Song Kim | Korea Institute of Science and Technology (KIST) |
| Date | Time | Schedule |
|---|---|---|
| Day 1 (Oct 4th) | 12:00 ~ 13:00 | Registration |
| 13:00 ~ 13:10 | Opening Remark (Uhtaek Oh, KIST, Korea) | |
| 13:10 ~ 15:50 | Session 1: Pain in the complex systems (Chair: Seog Bae Oh) |
|
| 13:10 ~ 14:00 | Cortical LTPs as key mechanisms for chronic pain and anxiety (Min Zhuo, Toronto Univ., Canada) *Video Conferencing |
|
| 14:00 ~ 14:50 | Structural plasticity in neural pathways and peripheral miswiring of sensory end organs in neuropathic pain (Rohini Kuner, Heidelberg Univ., Germany) *Video Conferencing |
|
| 14:50 ~ 15:20 | Developing fMRI-based biomarkers for pain (Choong-Wan Woo, IBS, Korea) |
|
| 15:20 ~ 15:50 | Neuroimmune crosstalk in peripheral neuropathy : role of natural killer cells (Seog Bae Oh, Seoul Natl. Univ., Korea) |
|
| 15:50 ~ 16:10 | Coffee Break | |
| 16:10 ~ 18:00 | Session 2: Mechanobiology (Chair: Yan Jie) | |
| 16:10 ~ 17:00 | The mechanical activation of talin and vinculin (Yan Jie, Natl. Univ. of Singapore, Singapore) |
|
| 17:00 ~ 17:30 | Integrin activation by membrane tension (Chungho Kim, Korea Univ., Korea) |
|
| 17:30 ~ 18:00 | Nuclear Mechanobiology: Biological interpretation of subcellular nuclear mechanics (Donghwee Kim, Korea U) |
|
| 18:00 ~ 21:00 | Welcome Dinner (Gangneung City) | |
| Day 2 (Oct 5th) | 09:30 ~ 12:50 | Session 3: Ion channels in pain (Chair: Myungha Yoon) |
| 09:30 ~ 10:10 | Anoctamin 1 in itch and pain (Uhtaek Oh, KIST, Korea) |
|
| 10:10 ~ 11:00 | TRP channels and Pain (Makoto Tominaga, NIPS, Japan) |
|
| 11:00 ~ 11:30 | New TRP channel tuner GPRs for pain modulation (Sun Wook Hwang, Korea Univ., Korea) |
|
| 11:30 ~ 12:20 | From genes to analgesic drugs (John N Wood, Univ. College London, UK) |
|
| 12:20 ~ 12:50 | Nav1.7 blockers for pain treatment (Woongbin Kim, iN Therapeutics, Korea) |
|
| 12:50 ~ 14:10 | Luncheon | |
| 14:10 ~ 18:00 | Session 4: Mechanosensitive ion channels (1) (Chair: Uhtaek Oh) | |
| 14:10 ~ 15:00 | Next generation gene therapies for genetic hearing loss (Jeffrey Holt, Harvard Univ., USA) *Video Conferencing |
|
| 15:00 ~ 15:50 | Feeling force with PIEZOs (Bailong Xiao, Tsing Hua Univ., China) Video Conferencing |
|
| 15:50 ~ 16:40 | Collective behavior of force-gated ion channels (Eric Honoré, CNRS, France) |
|
| 16:40 ~ 17:10 | Mechanosensitive piezo channel, PIEZO-1, regulates food deglutition in C. Elegans (Kyuhyung Kim, DGIST, Korea) |
|
| 17:10 ~ 18:00 | Tentonin 3, a mechanosensitive channel: its biophysics and physiology (Uhtaek Oh, KIST, Korea) |
|
| 18:00 ~ 21:00 | Dinner (Gangneung City) | |
| Day 3 (Oct 6th) | 09:30 ~ 12:10 | Session 5: Mechanosensitive ion channels (2) |
| (Chair: C. Justin Lee) | ||
| 09:30 ~ 10:20 | 3.8 billion years of mechanosensory transduction: 'What is true for E. coli true for the elephant' (Boris Martinac, Victor Chang Cardiac Res. Inst., Australia) |
|
| 10:20 ~ 11:10 | Ultrasonogenetic neuromodulation via astrocytic TRPA1 (C. Justin Lee, IBS, Korea) |
|
| 11:10 ~ 11:40 | Tentonin 3 and cytoskeletons (Gyu-Sang Hong, KIST, Korea) |
|
| 11:40 ~ 12:10 | In vitro analysis of the electrophysiological characteristics of mechanosensitive ion channel: Tentonin 3/TMEM150c (Taesong Kim, KIST, Korea) |
|
| 12:10 ~ 13:00 | Luncheon | |
| 13:00 ~ 18:00 | Excursion (Goseong DMZ) | |
| 18:00 ~ 21:00 | Banquet (Gangneung City) | |
| Day 4 (Oct 7th) | 10:00 ~ 11:50 | Group Discussion & Farewell |
| 11:50 ~ 12:00 | Closing Remark (Uhtaek Oh, KIST, Korea) |